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dc.contributor.advisorPeña Rodas, Oscar-
dc.contributor.advisorHernández Rauda, Roberto-
dc.contributor.advisorMartínez López, Roxana-
dc.date.accessioned2023-06-20T23:31:10Z-
dc.date.available2023-06-20T23:31:10Z-
dc.date.issued2020-09-01-
dc.identifier.otherhttps://doi.org/10.1016/j.toxrep.2020.08.031-
dc.identifier.urihttp://redicces.org.sv/jspui/handle/10972/4755-
dc.descriptionInforme derivadoes_ES
dc.description.abstractAflatoxin M1 is a carcinogenic and genotoxic metabolite of Aflatoxins present in food contaminated by fungi for lactating cattle, it is excreted through milk and when used to make cheese, the toxin will also be transferred to the dairy. The contamination of unripened hard white cheese with AFM1 seems to vary according to the season of the year, possibly due to the change of foodstuff, from fresh pasture in the rainy season to dried foods in the dry season and vice versa. This research determined both the prevalence and contents of AFM1 in cheeses of local and Nicaraguan origin marketed in El Salvador, as well as the changes occurred according to the season and the association between levels of AFM1 with meteorological parameters. The significantly higher prevalence of AFM1 contamination in both local cheeses and Nicaraguans, was found in the dry season and the lowest in the rainy season (41 % vs. 20 %; 31 % vs. 0%, respectively), the same trend was observed in AFM1 contents (0.076 vs. 0.036 μg/kg; 0.050 vs. 0.021 μg/kg, respectively). A significant association was demonstrated between levels of AFM1 with the averages of accumulated rainfall and relative humidity according to the sampled season. The prevalence of AFM1 in cheeses indicate that El Salvador and Nicaragua are endemic to dairy contamination by that mycotoxin. Seasonal variation may be due to a lack of rainfall, that promotes the growth of aflatoxigenic fungi in the crops of raw materials, which will be used for feedstuff intended for dairy cattle, thus, the consumption of contaminated food will cause the temporary increase of AFM1 in milk and their derivatives.es_ES
dc.description.sponsorshipUniversidad Doctor Andrés Belloes_ES
dc.format.extent26es_ES
dc.format.mimetypepdfes_ES
dc.language.isoenes_ES
dc.publisherUniversidad Doctor Andrés Belloes_ES
dc.relation.ispartofInforme derivado del artículo "Aflatoxin M1 in Nicaraguan and locally made hard white cheeses marketed in El Salvador", para la zona centrales_ES
dc.relation.ispartofseriesSS/INV/C/2020es_ES
dc.rights© 2020 Universidad Doctor Andres Bello. Published by Elsevier B.V. This is an open access article under the CC BY-NC-ND license.es_ES
dc.subjectAFM1es_ES
dc.subjectAflatoxin M1es_ES
dc.subjectAFB1, Aflatoxin B1es_ES
dc.subjectAFs, Total Aflatoxins (B1+B2+G1+G2)es_ES
dc.subjectELISA, Enzyme-linked immunosorbent assayes_ES
dc.subject%RSD, Coefficient of variationes_ES
dc.subjectHORRAT, Horwitz ratio.es_ES
dc.titleAflatoxin M1 in Nicaraguan and locally made hard white cheeses marketed in San Salvador, El Salvador.es_ES
dc.typeBookes_ES
dc.type.versionVersion publicadaes_ES
dc.rights.accessRightsLibre accesoes_ES
Aparece en las colecciones: Salud (UNAB)

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